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Clinical Uses of Oral Osteoinductive Protein Complex: Meeting the unmet medical need in bone and cartilage management

Clinical Uses of Oral Osteoinductive Protein Complex: Meeting the unmet medical need in bone and cartilage management

October 31, 2018

While there are a number of dietary supplements on the market that support bone and cartilage health, there is still an unmet medical need in relation to products that stimulate the growth of new bone and cartilage tissue.* Supplements such as calcium, D3, and K2 help fortify tissue, which sustain or enhance its physiological state, but does not propagate new tissue growth. While these types of nutrients do provide some of the building blocks for bone and cartilage, how these nutrients are utilized, and what stimulates the growth and development of the tissue itself, is a critical question. 

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Clinical Rounds Educational Series: Growing de novo bone & cartilage tissue

Osteoinductive Protein Complex: Growing de novo bone and cartilage tissue via stem cell activation

October 31, 2018

The term osteoinduction refers to the differentiation of stem cell (SC) progenitors into osteoblasts and chondrocytes. This process is regulated by a group of proteins in the transforming growth factor-ß (TGF-ß) superfamily knowns as bone morphogenetic proteins (BMPs). Specifically, this signaling pathway propagates bone and cartilage matrix synthesis (tissue) through osteoblast and chondrocyte differentiation, which subsequently promotes de novo bone growth and cartilage formation. 

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